On-body Injector Patient Instructions for Use:

Which version of the Instructions for Use did your doctors's office give you?

I have this folded version

I have this full-color booklet version

If you don’t recognize the images above or if you prefer a physical copy, contact your doctor.

Onpro® Kit HCP Instructions for Use:

Which version of the Instructions for Use came with your patient's on-body injector?




This version




This version

Indication

Neulasta® (pegfilgrastim) is a prescription medicine used to help reduce the... Read More

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~1 million patients have received Neulasta® Onpro®

Neulasta® Onpro® reduces the risk of febrile neutropenia without having to go back to the doctor's office*

Some patients find it hard to return to their physician the next day to receive Neulasta®, and missing a dose of Neulasta® can increase the risk of febrile neutropenia. With Onpro®, patients can receive Neulasta® at home so they don't have to go back to the doctor on the day after chemo.

Neulasta® Onpro® may be able to help
with these common challenges

For many patients, there’s no place like home the day after chemo. There’s no reason to make trips back to the doctor if you can stay at home instead. Ask your doctor if Neulasta® Onpro® is right for you.

Neulasta® Onpro® may be right for you if you are an adult, are comfortable with the patient instructions for use, and have no allergies to acrylics.

Exposure to viruses
People with a weakened immune
system may want to stay away
from those with a viral infection.

Social Distancing
Struggle to get transportation

Struggle to get transportation
For some, getting a ride can be difficult.

Live far away
Driving is part of the
time you
spend going
to an appointment.

Live far away
On Body Injector
One less trip back to the doctor’s office

One less trip back to
the doctor’s office
 Neulasta® Onpro® was
designed so you can stay home* to get your dose.

Bad weather
Avoid the elements and
dangerous conditions.

Bad weather
Chemo before holidays & weekends

Chemo before
holidays & weekends
Chemo on a day before
next-day office closings.

* If, for any reason, you believe you did not receive your full dose of Neulasta® or that your on-body injector is not working correctly, immediately contact your healthcare provider, as an incomplete dose could increase infection risk.

How the Neulasta® Onpro®
on-body injector works

Right after your strong chemo treatment, your healthcare provider will apply the on-body injector to your skin. The on-body injector is designed to automatically deliver your Neulasta® dose over 45 minutes, approximately 27 hours after application. Once your dose is complete, remove the injector and dispose of it according to the Patient Instructions for Use.

The summary does not replace the Patient Instructions for Use. If you are using Neulasta® Onpro®, it’s
important that you review the patient instructions and call your doctor if you have any questions.

On Body Injector

Applying and removing the on-body injector

Watch this overview video to learn more about how your healthcare provider will apply the Neulasta® Onpro® on-body injector, how it is removed, and what to expect the next day.

This video does not replace the instructions for use. Please consult the instructions for
use when using the Neulasta® Onpro® kit.

To watch this video in Spanish, click here.

A PodPal™ adds extra adhesion

PodPals Image

For a more secure fit, an adhesive extender that fits around the on-body injector called a PodPal™ may be added by your doctor or nurse if they deem it appropriate. You can also ask your doctor or nurse about adding a PodPal™ when they put your Onpro® on-body injector in place.

Used by ~1 million patients

Neulasta® Onpro® is designed to automatically deliver Neulasta® the next day—so you don't have to leave your home to go back to the doctor's office.

What patients think

95 percent

95% of patients would choose Onpro® again

Before your first round of chemo, ask your doctor if Neulasta® Onpro® can be part of your treatment plan.

Explore Tools & Resources

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Already using Onpro®?
Get practical tools that can help you through the process.

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Learn how you
could pay $5 or
less per dose*

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Download the Doctor
Discussion Guide

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*For commercially insured
patients, up to annual limit.

Important Safety Information

Do not take Neulasta® if you have had a serious allergic reaction to pegfilgrastim or filgrastim.

Before you receive Neulasta®, tell your healthcare provider about all of your healthcare conditions, including if you:
  • Have a sickle cell disorder
  • Have had severe skin reactions to acrylic adhesives
  • Are allergic to latex – The needle cap on the prefilled syringe contains dry natural rubber (derived from latex).
  • Have kidney problems
  • Are pregnant or plan to become pregnant. It is not known if Neulasta® may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if Neulasta® passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible serious side effects of Neulasta®?
  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta®. A ruptured spleen can cause death. Call your healthcare provider right away if you have pain in the left upper stomach area or left shoulder tip area.
  • A serious lung problem called Acute Respiratory Distress Syndrome (ARDS). Call your healthcare provider or get emergency medical help right away if you have shortness of breath with or without a fever, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Neulasta® can cause serious allergic reactions. These reactions can cause a rash over your whole body, shortness of breath, wheezing, dizziness, swelling around your mouth or eyes, fast heart rate and sweating.
If you have an allergic reaction during the delivery of Neulasta®, remove the on-body injector for Neulasta® by grabbing the edge of the adhesive pad and peeling off the on-body injector. Get emergency medical help right away.
  • Sickle Cell Crises. You may have a serious sickle cell crisis, which could lead to death, if you have a sickle cell disorder and receive Neulasta®.
  • Kidney injury (glomerulonephritis). Neulasta® can cause kidney injury. Call your healthcare provider right away if you develop any of the following symptoms: swelling of your face or ankles, blood in your urine or dark colored urine, or you urinate less than usual.
  • Increased white blood cell count (leukocytosis). Your healthcare provider will check your blood during treatment with Neulasta®.
  • Decreased platelet count (thrombocytopenia). Your healthcare provider will check your blood during treatment with Neulasta®. Tell your healthcare provider if you have unusual bleeding or bruising during treatment with Neulasta®. This could be a sign of decreased platelet counts, which may reduce the ability of your blood to clot.
  • Capillary Leak Syndrome. Neulasta® can cause fluid to leak from blood vessels into your body’s tissues. This condition is called "Capillary Leak Syndrome" (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
    • Swelling or puffiness and are urinating less than usual
    • Trouble breathing
    • Swelling of your stomach area (abdomen) and feeling of fullness
    • Dizziness or feeling faint
    • A general feeling of tiredness
  • Myelodysplastic syndrome and acute myeloid leukemia. If you have breast cancer or lung cancer, when Neulasta® is used with chemotherapy and radiation therapy, or with radiation therapy alone, you may have an increased risk of developing a precancerous blood condition called myelodysplastic syndrome (MDS) or a blood cancer called acute myeloid leukemia (AML). Symptoms may include tiredness, fever, and easy bruising or bleeding. Call your healthcare provider if you develop these symptoms during treatment with Neulasta®.
  • Inflammation of the aorta (aortitis). Inflammation of the aorta (the large blood vessel which transports blood from the heart to the body) has been reported in patients who received Neulasta®. Symptoms may include fever, abdominal pain, feeling tired, and back pain. Call your healthcare provider if you experience these symptoms.

The most common side effect of Neulasta® is pain in your bones and in your arms and legs.

These are not all the possible side effects of Neulasta®. Call your healthcare provider for medical advice about side effects. You may report negative side effects to the FDA at 1-800-FDA-1088.

Please see Neulasta® Patient Information.

Neulasta® Injection: 6 mg/0.6 mL in a single-dose prefilled syringe for manual use only.

Neulasta® Injection: 6 mg/0.6 mL in a single-dose prefilled syringe co-packaged with the on-body injector (OBI) for Neulasta® (Neulasta® Onpro® kit).

Important Safety Information
Do not take Neulasta® if you have had a serious allergic reaction to pegfilgrastim or filgrastim.
Before you receive Neulasta®, tell your healthcare provider about all of your healthcare conditions, including if you:
• Have a sickle cell disorder
• Have had severe skin reactions to acrylic adhesives